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| Employer | # of Employees |
|---|---|
| Mission CISD | 2,412 |
| Sharyland ISD | 1,168 |
| Mission Regional Medical Center | 950 |
| T-Mobile | 904 |
| H.E.B Grocery | 684 |
| City of Mission | 641 |
| Wal-Mart Super Center | 383 |
| Haliburton Energy Services | 200 |
| Target | 165 |
| Club at Cimarron | 150 |
| Home Depot | 132 |
| Texas Citrus Exchange (TCX) | 130 |
| Whataburger | 97 |
| Mission Paving Co. Inc. | 87 |
| Hi-Tech Plastics, Rio Grande, L.P. | 80 |
| Foy’s Supermarket | 80 |
| K-Mart Stores | 79 |
| Mission Shippers | 70 |
| Frito-Lay, Inc. | 62 |